New malaria drug packs a triple punch – health – 25 March 2013 – New ScientistPosted: March 27, 2013
The drug, called ELQ-300, wrecks the parasites’ ability to reproduce by disabling their mitochondria, the factories that produce two of the building blocks they need to make DNA. The drug does not harm human mitochondria, which produce energy rather than DNA.
ELQ-300 rapidly cured infected mice and killed parasites in mosquitoes that were allowed to feed on the mice shortly after infection, blocking further transmission to new victims.
Riscoe says that if ELQ-300 passes the obligatory safety tests, trials could begin in humans within two years.