Malaria Transmission-blocking Vaccine Assessment

The TBV Pfs25 approach aims to block malaria from being transmitted from mosquitoes to humans by preventing the malaria parasite from developing in the mosquito, and although such a vaccine would not directly protect an immunized individual from developing clinical malaria, it would reduce the chances that others in the community contract malaria by preventing the spread of infection by the mosquito.

A transmission-blocking vaccine (TBV) would work in combination with drugs and insecticides by blocking the transmission of the parasite. This would decrease the demand on other measures, therefore slowing the development of resistance and subsequently extend their effectiveness.

via Malaria Transmission-blocking Vaccine Assessment.

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