Study Suggests Dormant Malaria Parasites in Red Blood Cells May Contribute to Treatment Failure

Researchers at the University of South Florida (USF) College of Public College Health have shown for the first time in a rodent model that the earliest form of malaria parasites can lay dormant in red blood cells and “wake up,” or recover, following treatment with the antimalarial drug artesunate.

The study, which appears today in the online journal PLoS ONE, suggests that this early-stage dormancy phenomenon contributes to the failure of artesunate alone, or even combined with other drugs, to eliminate the mosquito-borne disease.  Alexis LaCrue, PhD, research associate in the USF Department of Global Health, is the lead author of the study, which was funded by the National Institute of Allergy and Infectious Diseases (NIAID).

via Study Suggests Dormant Malaria Parasites in Red Blood Cells May Contribute to Treatment Failure.

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